Namrata Misra

Associate Professor

Dr. Misra received her Master’s Degree from Banaras Hindu University and PhD in Life Sciences from Academy of Scientific and Innovative Research (AcSIR); CSIR-IMMT and Post Doctorate fellowship from Science and Engineering Research Board,DST Government of India. Her research focuses is on study of vital metabolic pathways and in-depthsequence-structural analysis of underpinning enzymes and their functional annotation using computational approach. The lab performs comparative phylogenomic across diverse microalgal genomes in order to identify putative lipid biosynthetic enzymes which are potential genetic engineering targets for improved algal biofuel production and also to unravel the evolution of animal and plant genomes on the large scale. It has been observed that more complete and valuable information about the function of enzymes can be gained if the sequences and structures are examined more thoroughly by employing various bioinformatics tools and databases. She along with her team members are also working on the development of various cutting-edge computations tools, databases and webservers to systematically analyzeand derive knowledge from massive biological sequence data accumulating from genomics project in order to improve understanding of various metabolic processes and to facilitate further experimental research by providing computational predictions. Currently, Dr. Misra lab is Implementing immunoinformatic and reverse vaccinology approaches for identification of immunogenic B and T cell epitopes which are potential future candidates for development of peptide-based vaccines to combat multiple infectious diseases. All selected promiscuous epitopes are studied computationally to know their immunogenicity, antigenicity, allergenicity, conservancy and toxicity potentials for the development of chimeric subunit vaccine

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Email :
[email protected]
Scopus Id :
57214422746
Google Scholar :
https://scholar.google.com/citations?hl=en&view_op=list_works&gmla=AJsN-F4PKcXTEZqM9X3kI9c_2vKPYJn8eQmQus5SUYnwoFeIB3yHFlIHyCwZilHXb2pka3fb-DW-e7qXrS26RBkkvuQNjBuJkA&user=_hFwumkAAAAJ

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Educational Qualification
  1. MSc Bioinformatics, Banaras Hindu University,
  2. PhD Life Sciences
  3. Academy of Scientific and Innovative Research (AcSIR); CSIR-IMMT Postdoc Bioinformatics
  4. NPDF-DST, Science and Engineering Research Board


Projects
Bioinformatic characterization of TAG competitive enzymes in microalgae with potential value for biofuel production, funded by Department of Science & Technology

Administrative Responsibility
Besides her core experience in research and development, Dr. Misra has been actively involved in promoting innovations in life science and start-up ecosystem across East and North East, specifically in the state of Odisha as Head-Bioinnovation at KIIT-Technology Business Incubator, KIIT University. She is responsible for employing her science knowledge in accelerating tech-innovations and help start-ups in translating their research ideas into marketable products having societal impact. She regularly conducts skill development programs in collaboration with various government funding agencies and also industry experts for capacity building of young innovators and to explore possible partnerships with other organizations for strengthening cooperation in S&T and innovation.
  1. Head-Bioinnovation, KIIT-Technology Business Incubator, Bhubaneswar
  2. Coordinator of Biotechnology Innovation Grant (BIG), a start-up funding program of BIRAC, DBT, Govt of India of up to 50 Lakhs for prototype development at KIIT-TBI
  3. Coordinator of BIRAC Regional Techno Entrepreneurship Promotion Centre to promote innovation and entrepreneurship across East and North East
  4. Member of Technology Enabling Centre of KIIT University to promote translation of research outcomes form Universities and to foster institute-academia collaboration.


Awards & Honours
  1. Recipient of National- Post Doctoral Fellowship under DST-Science and Engineering Research Board, 2017
  2. Recipient of Senior Research Fellow 2012, Council of Scientific and Industrial Research, Govt. of India, New Delhi, India
  3. Received Best Research Scholar award by CSIR-Institute of Minerals and Materials Technology,
  4. Life Science Editor of various renowned scientific journal editing companies like Cactus Communications and Manuscript Edit.


Memberships
  1. Head-Bioinnovation, KIIT-Technology Business Incubator, Bhubaneswar
  2. Coordinator of Biotechnology Innovation Grant (BIG), a start-up funding program of BIRAC, DBT, Govt of India of up to 50 Lakhs for prototype development at KIIT-TBI
  3. Coordinator of BIRAC Regional Techno Entrepreneurship Promotion Centre to promote innovation and entrepreneurship across East and North East
  4. Member of Technology Enabling Centre of KIIT University to promote translation of research outcomes form Universities and to foster institute-academia collaboration.


Outreach Activity
As Head Bioinnovations at KIIT TBI , Dr Misra is constantly engaged in capacity building and skill development programs supported by various government bodies tp promote innovation and entrepreneurship
Journals/Conferences :
1) S. Mahapatra, S. Sahoo, B. Dehury, V. Raina, S. Patro, N. Misra, M. Suar. Designing an Efficient Multi-Epitope Vaccine Displaying Interactions with Diverse HLA Molecules for an Efficient Humoral and Cellular Immune Response to prevent COVID-19 infection., Expert Rev. Vaccines. (2020). https://doi.org/10.1080/14760584.2020.1811091.
2) B. Dehury, V. Raina, N. Misra, M. Suar, Effect of mutation on structure, function and dynamics of receptor binding domain of human SARS-CoV-2 with host cell receptor ACE2: a molecular dynamics simulations study, J. Biomol. Struct. Dyn. (2020). https://doi.org/10.1080/07391102.2020.1802348.
3) Sahoo, S., Mahapatra, S. R., Parida, B. K., Narang, P. K., Rath, S., Misra, N., & Suar, M. (2020). dEMBF v2. 0: An Updated Database of Enzymes for Microalgal Biofuel Feedstock. Plant and Cell Physiology, 61(5), 1019-1024.
4) Arunima, S. K. Swain, S. D. Patra, S. Das, N.K. Mohakud, N. Misra, M. Suar. Role of OB Fold protein YdeI in stress response and virulence of Salmonella enterica serovar Enteritidis. Journal of Bacteriology (2020)
5) Kangabam R, Sahoo S, Ghosh A, Roy R Silla Y, Misra, N., & Suar, M. (2020). Next-Generation Computational Tools and Resources for Coronavirus Research: from Detection to Vaccine Discovery. Computers in Biology and Medicine (Accepted)
6) Sahoo, S Mahapatra, SR, Parida B, Dehury, B., Raina, V., Mohakud N, Misra, N., & Suar, M. (2020). DBCOVP: A Database of Coronavirus Virulent glycoProteins. Computers in Biology and Medicine (Accepted)
7) Sahoo, S., Mahapatra, S. R., Das, N., Parida, B. K., Rath, S., Misra, N., & Suar, M. (2020). Functional elucidation of hypothetical proteins associated with lipid accumulation: Prioritizing genetic engineering targets for improved algal biofuel production. Algal Research, 47, 101887.
8) Misra N, Mishra BK, Parida BK, Panda PK. Way forward to achieve sustainable and cost-effective biofuel production from microalgae: a review. International journal of Environmental Science and Technology, 2016,13(11); 10.1007/s13762-016-1020-5
9) Misra N, Panda PK, Parida BK, Mishra BK. dEMBF: A Comprehensive Database of Enzymes of Microalgal Biofuel Feedstock. Plos One, 2016, 11(1):e0146158.doi:10.1371/journal.pone.0146158
10) Parida BK, Panda PK, Misra N, Mishra BK.MaxMod: A HMM based novel interface to MODELLER for improved prediction of protein 3D models. Journal of Molecular Modeling, 2015, 21, 30-39
11) Misra N, Panda PK, Parida BK. Genome-wide identification and evolutionary analysis of algal LPAT gene involved in TAG biosynthesis using bioinformatic approaches. Molecular Biology Reports, 2014, 17, doi: 10.1007/s11033-014-3733-1
12) Parida BK, Panda S, Misra N, Panda PK, Mishra BK. BBProF: An Asynchronous Application Server for rapid Identification of Proteins associated with Bacterial Bioleaching. Geomicrobiology, 2013, doi: 10.1080/01490451.2013.826751
13) Misra N, Panda PK, Parida BK. Agrigenomics for Microalgal Biofuel Production: An Overview of Various Bioinformatics Resources and Recent Studies to Link OMICS to Bioenergy and Bioeconomy. OMICS: A Journal of Integrative Biology, 2013, 17, doi: 10.1089/omi.2013.0025
14) Misra N, Panda PK, Patra MC, Pradhan SK, Mishra BK. Insights into Molecular Assembly of ACCase Heteromeric Complex in Chlorella variabilis- A Homology Modelling, Docking and Molecular Dynamic Study. Applied Biochemistry and Biotechnology, 2013, doi: 10.1007/s12010-013-0277-0
15) Misra N, Panda PK. In Search of Actionable Targets for Agrigenomics and Microalgal Biofuel production: Sequence-Structural Diversity Studies on Algal and Higher Plants with a Focus on GPAT Protein. OMICS: A Journal of Integrative Biology, 2013, 17, 173-186, doi: 10.1089/omi.2012.0094
16) Misra N, Patra MC, Panda PK, Sukla LB, Mishra BK. Homology Modeling and Docking Studies of FabH (β-ketoacyl-ACP synthase III) Enzyme Involved in type II Fatty Acid Biosynthesis of Chlorella variabilis: a Potential Algal Feedstock for Biofuel Production. Journal of Biomolecular Structure and Dynamics, 2013, 31, 241-257, doi: 10.1080/07391102.2012.698247
17) Misra N, Panda PK, Parida BK, Mishra BK. Phylogenomic Study of Lipid genes Involved in Microalgal Biofuel Production-Candidate Gene Mining and Metabolic Pathway Analyses. Evolutionary Bioinformatics, 2012, 8, 545-564, doi:10.4137/EBO.S10159


Books :
Sahoo, S., Sahu, S. N., kumar Pattanayak, S., Misra, N., & Suar, M. (2020). Biosensor and its implementation in diagnosis of infectious diseases. In Smart Biosensors in Medical Care (pp. 29-47). Academic Press.
Sahoo, S., Mahapatra, S. R., Misra, N., & Suar, M. (2020). Application of Genomics, Transcriptomics and Proteomics in Probiotic Research, in Probiotic Beverages